Biofiller

What is this treatment?

In some procedures, biofiller refers to gel prepared from the plasma part of blood. Autologous means the person is their own source. Preparation methods differ; not every gel should be called fibrin or PRP.

A small clinical study of plasma gel reports short-term findings. However, such data do not establish long-term effects or exclude rare risks. Promises of tissue regeneration or permanent volume are therefore inappropriate.

Who may be suitable?

Adults exploring options for facial volume loss or fine lines may seek assessment. However, not every under-eye hollow or colour change needs the same approach. Allergy to hyaluronic acid does not automatically make biofiller suitable.

Disclose blood disorders, bleeding problems, active infection and medicines. Also share ongoing cancer treatment, pregnancy and breastfeeding. Treatment may be postponed when safety is uncertain or a health problem is present.

How is it performed?

1. Assessment: First discuss the concern, alternatives and reason for using a blood-derived material.
2. Blood collection: If appropriate, the healthcare team takes a blood sample.
3. Preparation: The team separates plasma and prepares the material according to the method. Ask about added substances and sterile preparation.
4. Injection: The practitioner places the material in the planned area. They then explain care, reviews and emergency arrangements.

Recovery

Bruising, tenderness or swelling may occur at blood collection and injection sites. Follow care instructions and do not rub the area on your own initiative. Also ask about returning to work and exercise.

Initial swelling may exaggerate the volume change. Therefore, do not treat the early appearance as a lasting result. Swelling duration varies individually. Review benefits and unexpected symptoms at follow-up; do not assume automatic repeat sessions or a fixed duration of effect.

Risks and side effects

Possible problems include infection, bleeding, irregularities and persistent swelling. Substances used during preparation or local anaesthetics may also cause reactions. Using your own blood does not remove these risks.

Serious vascular problems and vision loss have been reported after facial injections of autologous blood products. However, these reports do not establish a risk rate for every biofiller method. Seek emergency care for visual changes, unusual pain or sudden white, grey or blue skin discolouration. Do not wait for review. Also promptly report increasing redness, discharge or fever.